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<NewsItem contentIssues="true" id="56849" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/56849">
<Title>Leach &amp; White develop sensors for real-time drug monitoring</Title>
<Tagline>Team awarded $1.2M in funding from NIH</Tagline>
<Body>
<![CDATA[
    <div class="html-content"><span>The ability to provide real-time information about an individual's response to therapeutics has the potential to revolutionize healthcare by offering personalized treatment. Drugs with narrow therapeutic windows become toxic or ineffective if over- or under-dosed. Maintaining the most efficient dosage, personalized to the patient, can reduce toxicity, maximize efficacy of treatment, and ultimately improve patient outcome.<br><br>In order to address this need, Jennie Leach and Ryan White (UMBC Chemistry) are developing a new class of electrochemical biosensors capable of providing continuous real-time therapeutic drug monitoring with unprecedented chemical specificity and temporal resolution. This project leverages state-of-the-art bioanalytical science (White Lab) with biocompatible material engineering (Leach Lab) to develop hybrid aptamer-hydrogel sensors capable of real-time continuous therapeutic drug monitoring in patients. This work was recently funded by the NIH.<br></span><div><br></div><div>Read more below!</div></div>
]]>
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<Summary>The ability to provide real-time information about an individual's response to therapeutics has the potential to revolutionize healthcare by offering personalized treatment. Drugs with narrow...</Summary>
<Website>https://projectreporter.nih.gov/project_info_description.cfm?aid=9006465&amp;icde=27342202</Website>
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<PostedAt>Mon, 04 Jan 2016 19:32:57 -0500</PostedAt>
<EditAt>Mon, 04 Jan 2016 19:33:41 -0500</EditAt>
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<NewsItem contentIssues="true" id="56765" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/56765">
<Title>Ghosh/Sowers project featured on Quantico Base news site</Title>
<Tagline>research aims to prevent PCBs from entering food chain</Tagline>
<Body>
<![CDATA[
    <div class="html-content"><div>
        <strong>Marine Corps Base Quantico --<br><br></strong>
        <p>The murky waters at Abraham’s Creek at Marine Corps Base Quantico
     have the potential to provide a solution to the problem of 
    polychlorinated biphenyls (PCBs) entering the food chain.</p>
    <p>The creek is the location of a year-long study conducted by 
    scientists at University of Maryland Baltimore County and funded by the 
    Department of Defense’s Environmental Security Technology Certification 
    Program (ESTCP). </p>
    <p>On Tuesday, Sept. 15, the scientists made their fourth visit to 
    Abraham’s Creek to collect 12-inch core samples of the sediment at the 
    creek bottom. They also deployed 16 square sheets of polyethylene 
    plastic throughout the creek to collect PCB particles in order to 
    measure their prevalence.</p>
    <p>PCBs are stabilizing, long-lasting chemicals that were used in many 
    products prior to being banned in the 1970s, explained Dr. Kevin Sowers,
     Professor at UMBC’s Institute of Marine and Environmental Technology 
    and one of the scientists on the team.</p>
    <p>“There are lots of sources of PCBs,” Sowers said. “They were used in 
    paints, in caulks, in carbonless copy paper, in oil to reduce its 
    flammability.”</p>
    <p>The team identified the Abraham’s Creek site with input from ESTCP. 
    It’s not clear what caused the levels of PCBs in Abraham’s Creek, but 
    Sowers theorises that decades-old pesticides are the culprit. PCBs were 
    also used as extenders in pesticides.</p>
    <p>PCBs are primarily exposed to the ecosystem through clams, snails, 
    and worms that live in muddy sediment, explained Dr. Upal Ghosh, 
    Professor of Chemical, Biochemical, and Environmental Engineering at 
    UMBC, another member of the team. </p>
    <p>“Fish then eat these small animals. Therefore, human exposure to PCBs is often through fish,” he said. </p>
    <p>Ghosh and Sowers said that PCBs are probable carcinogens, because 
    there is evidence that rats develop cancer when exposed to high levels. 
    PCBs are also teratogens (agents that disrupt the development of a fetus
     in the womb), endocrine disrupters, and neurotoxins. They do not, 
    however, affect the physical environment.</p>
    <p>“If we can block the availability of the PCBs to the food chain, 
    that’s more relevant than getting the overall levels down,” Sowers said.</p>
    <p>The team has discovered a potential way to accomplish this, using a combination of carbon and helpful microorganisms.</p>
    <p>“The PCBs absorb to the carbon, kind of like what a Brita filter does when it filters water,” Ghosh explained.</p>
    <p>Anaerobic microorganisms, which do not require oxygen for breathing or growth, are then introduced.</p>
    <p>“PCBs are made up of chlorine attached to two rings of benzene,” 
    Sowers explained. “The anaerobes use the chlorine in the PCBs to 
    respirate. Once they’ve clipped the chlorine from the benzene rings, 
    aerobes — organisms that require oxygen — can then degrade the 
    chlorine.”</p>
    <p>These methods worked in the lab, and the team hopes they will work in the real world as well.</p>
    <p>Earlier this year, the team set up four plots in Abraham’s Creek — a 
    control area and three test plots. They treated one of the test plots 
    with activated carbon and one with carbon and microorganisms. At their 
    visit last week, they pulled core samples from the different plots and 
    distributed polyethylene sheets to absorb the PCBs and measure their 
    levels. They will return in October or early November to collect the 
    sheets. After that, it will take about 30 days to process the data. </p>
    <p>Pending the results, the goal is to write a peer-reviewed paper for submission to an environmental journal.</p>
    <p>— Writer: <a href="mailto:auphausconner@quanticosentryonline.com" rel="nofollow external" class="bo">auphausconner@quanticosentryonline.com</a></p>
        </div></div>
]]>
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<Summary>Marine Corps Base Quantico --        The murky waters at Abraham’s Creek at Marine Corps Base Quantico  have the potential to provide a solution to the problem of  polychlorinated biphenyls (PCBs)...</Summary>
<Website>http://www.quantico.marines.mil/News/NewsArticleDisplay/tabid/10834/Article/621620/abrahams-creek-site-of-year-long-study-by-scientists.aspx</Website>
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<Sponsor>Chemical, Biochemical and Environmental Engineering</Sponsor>
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<NewsItem contentIssues="false" id="56747" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/56747">
<Title>What do environmental engineers do?</Title>
<Body>
<![CDATA[
    <div class="html-content">CBEE students, Helena Gaifem, Nicholas Rogers, Utsav Shashvatt, Kiranmayi Mangalgiri, Hollie Adejumo, Hannah Aris, and Savannah Steinly, tell you in the following video:  <a href="https://www.youtube.com/watch?v=MUT8zya53Vg">https://www.youtube.com/watch?v=MUT8zya53Vg</a><div><br></div><div>Share their story, like the video, and promote their work!  They have a chance to win first prize in a national environmental engineering video competition.</div></div>
]]>
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<Summary>CBEE students, Helena Gaifem, Nicholas Rogers, Utsav Shashvatt, Kiranmayi Mangalgiri, Hollie Adejumo, Hannah Aris, and Savannah Steinly, tell you in the following video:...</Summary>
<Website>https://www.youtube.com/watch?v=MUT8zya53Vg</Website>
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<Sponsor>Chemical, Biochemical and Environmental Engineering</Sponsor>
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<PostedAt>Sat, 19 Dec 2015 19:20:55 -0500</PostedAt>
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<NewsItem contentIssues="true" id="56459" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/56459">
<Title>Dr. Theresa Good Honored by the AIChE</Title>
<Tagline>Former CBEE faculty wins Distinguished Service Award</Tagline>
<Body>
<![CDATA[
    <div class="html-content"><div><span>Dr. Theresa Good, </span><span>Former UMBC CBEE faculty member, currently </span><span>Deputy Division Director of the Division of Molecular and Cellular Biosciences at NSF was recognized by the American Institute of Chemical Engineers as the 2015 recipient of their prestigious Food, Pharmaceutical and Bioengineering Division Distinguished Service Award in Chemical Engineering. Recipients of this award have made an exceptional contribution to the profession </span><span>of food engineering, pharmaceutical engineering, and/or bioengineering in general.</span></div><div><br></div><div><br></div></div>
]]>
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<Summary>Dr. Theresa Good, Former UMBC CBEE faculty member, currently Deputy Division Director of the Division of Molecular and Cellular Biosciences at NSF was recognized by the American Institute of...</Summary>
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<NewsItem contentIssues="true" id="56074" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/56074">
<Title>CBEE undergrads attend AIChE poster competition</Title>
<Tagline>Apurva Shah wins 1st prize in Sustainability discipline</Tagline>
<Body>
<![CDATA[
    <div class="html-content">Congratulations to CBEE undergraduate students Michael Valerino, <br>
            Matthew Sweeney, and Apurva Shah, who presented their work at the <a href="http://www.aiche.org/conferences/annual-aiche-student-conference/2015" rel="nofollow external" class="bo">AIChE Annual Student Conference</a> poster competition on Monday, November 9th, 2015 in Salt Lake City, Utah. Apurva Shah brought home a 1st Place trophy in the Sustainability discipline for his poster entitled<em> Food-Energy-Water Nexus: Quantifying the energy and GHG emissions of water embodied in food flows with the U.S. </em><br><br>The Annual Student Conference is four days of career information, social
     events, competitions, and fun. Student engineers from more than 150 
    schools celebrate the Chemical Engineering profession, along with young 
    professional members, AIChE leaders, and industry professionals from 
    numerous engineering specialties.<br><br>With more than 350 students presenting last year and about 80 judges, it
     is the largest forum for Chemical Engineering undergraduates to present
     their research activity to the professional community at large.<br><br>Posters are judged by a panel of typically 3 or 4 AIChE professional members from academia and industry.<br><br><img src="http://my.umbc.edu/groups/cbee/posts/56074/attachments/18865" height="200" width="267" style="max-width: 100%; height: auto;"><br><br><br><img src="http://my.umbc.edu/groups/cbee/posts/56074/attachments/18870" height="202" width="270" style="max-width: 100%; height: auto;"><br><br><img src="http://my.umbc.edu/groups/cbee/posts/56074/attachments/18874" height="204" width="272" style="max-width: 100%; height: auto;"><br><br><img src="http://my.umbc.edu/groups/cbee/posts/56074/attachments/18869" height="222" width="269" style="max-width: 100%; height: auto;"><br><br><img src="http://my.umbc.edu/groups/cbee/posts/56074/attachments/18873" height="316" width="269" style="max-width: 100%; height: auto;"><br></div>
]]>
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<Summary>Congratulations to CBEE undergraduate students Michael Valerino,           Matthew Sweeney, and Apurva Shah, who presented their work at the AIChE Annual Student Conference poster competition on...</Summary>
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<NewsItem contentIssues="true" id="55852" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/55852">
<Title>CAST/CSEE/CBEE to help kids with asthma breathe more easily</Title>
<Tagline>team has received nearly $2 million award from NIH</Tagline>
<Body>
<![CDATA[
    <div class="html-content"><p>An innovative team of researchers working across engineering fields 
    has received a nearly $2 million award from the National Institutes of 
    Health (NIH) <a href="http://grants.nih.gov/grants/guide/rfa-files/RFA-EB-15-002.html" rel="nofollow external" class="bo">PRISMS program</a>
     to develop a comprehensive system to monitor critical environmental 
    asthma triggers and physiological status indicators for pediatric asthma
     patients.</p> 
    
    
    
    <p>The grant is led by UMBC’s Center for Advanced Sensor Technology (CAST). UMBC PIs <strong>Yordan Kostov</strong> and <strong>Govind Rao</strong>,
     assistant director and director of CAST, respectively, teamed up with 
    Southern Methodist University psychology professors and asthma experts <strong>Thomas Ritz</strong> and <strong>Alicia Meuret</strong>, as well as UMBC computer science and electrical engineering (CSEE) faculty <strong>Ryan Robucci</strong> and <strong>Nilanjan Banerjee</strong>, and chemical, biochemical, and environmental engineering (CBEE) faculty <strong>Xudong Ge</strong> and <strong>Chris Hennigan</strong>.</p>
    
    <p>The wearable asthma monitoring system they are developing will 
    include technology that measures environmental triggers, such as air 
    pollution, pollen, dust, smoke and pet hair, and a monitor that measures
     physiological triggers, such as level of physical activity and 
    emotional stress. <br></p>
    
    <p>The monitoring system will be small enough to be worn by the patient 
    in the form of a pendent, explains Yordan Kostov, research professor in 
    CBEE and adjunct professor in CSEE. <br></p><p><br></p><p><em>for complete story, see link below: </em><br></p><a href="https://news.umbc.edu/helping-kids-with-asthma-breathe-easier/" rel="nofollow external" class="bo">https://news.umbc.edu/helping-kids-with-asthma-breathe-easier/</a></div>
]]>
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<Summary>An innovative team of researchers working across engineering fields  has received a nearly $2 million award from the National Institutes of  Health (NIH) PRISMS program  to develop a comprehensive...</Summary>
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<PostedAt>Wed, 11 Nov 2015 13:42:00 -0500</PostedAt>
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<NewsItem contentIssues="true" id="55824" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/55824">
<Title>Blaney Lab nutrient recovery research highlighted by VOA</Title>
<Body>
<![CDATA[
    <div class="html-content">Ongoing research from the Blaney Lab was highlighted in a recent Voice of America News piece titled, "<a href="https://www.voanews.com/episode/search-solution-turning-manure-money-3704166" rel="nofollow external" class="bo">In Search of a Solution: Turning Manure Into Money</a>," by Steve Baragona.  Blaney's team is working with Triea Technologies and Chesapeake Bay farmers to develop new, innovative processes for extracting nutrients from agricultural waste and recovering value-added fertilizers.</div>
]]>
</Body>
<Summary>Ongoing research from the Blaney Lab was highlighted in a recent Voice of America News piece titled, "In Search of a Solution: Turning Manure Into Money," by Steve Baragona.  Blaney's team is...</Summary>
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<PostedAt>Tue, 10 Nov 2015 17:16:19 -0500</PostedAt>
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<NewsItem contentIssues="true" id="55643" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/55643">
<Title>Rao discusses "beyond revolutionary" portable bioreactors</Title>
<Tagline>Innovation developed to save lives on battlefields</Tagline>
<Body>
<![CDATA[
    <div class="html-content">From <a href="https://news.umbc.edu/%ef%bb%bf-govind-rao-discusses-portable-bioreactors-developed-to-save-lives-on-battlefields/" rel="nofollow external" class="bo">UMBC Insights</a>:<br><br><p>Soldiers on the battlefield and first-responders in conflict zones 
    will soon be able to save lives by using a portable, briefcase-sized 
    tool that rapidly manufactures medicines. Govind Rao, professor of 
    chemical and biochemical engineering and director of the Center for 
    Advanced Sensor Technology (CAST) at UMBC, leads the research team 
    behind this innovation. At the recent Bioprocess International 
    conference, he called the system “beyond revolutionary,” reports <a href="http://www.biopharma-reporter.com/Upstream-Processing/Beyond-revolutionary-bioreactor-in-a-briefcase-brings-warzone-production" rel="nofollow external" class="bo"><em>BioPharma</em></a>.
    </p><p>“Welcome to the Betty Crocker world of bioprocessing,” said Rao. “Within a few hours you are expressing a high quality protein.”</p><p>The product emerged from concerns that current methods for getting 
    pharmaceutical supplies to battlefields, often requiring airdrops, 
    needed to be replaced with point-of-care technology. The project is a 
    collaborative effort among multiple academic institutions and 
    corporations, and was funded by a $7.9 million grant from the U.S. 
    Defense Advanced Research Projects Agency. In the future, Rao hopes this
     technology can be applied to producing low-cost vaccines.</p><p>Read the full article, “‘Beyond revolutionary’: bioreactor-in-a-briefcase brings warzone production,” on <a href="http://www.biopharma-reporter.com/Upstream-Processing/Beyond-revolutionary-bioreactor-in-a-briefcase-brings-warzone-production" rel="nofollow external" class="bo"><em>BioPharma</em></a>.</p></div>
]]>
</Body>
<Summary>From UMBC Insights:   Soldiers on the battlefield and first-responders in conflict zones  will soon be able to save lives by using a portable, briefcase-sized  tool that rapidly manufactures...</Summary>
<Website>http://cast.umbc.edu/</Website>
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<PostedAt>Thu, 05 Nov 2015 11:19:15 -0500</PostedAt>
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<NewsItem contentIssues="true" id="55265" important="false" status="posted" url="https://my3.my.umbc.edu/groups/cbee/posts/55265">
<Title>Sensors class attends Pediatric Innovation Symposium</Title>
<Body>
<![CDATA[
    <div class="html-content">On October 23rd, Dr. Rao's Sensors class is attending the <a href="http://www.pediatric-surgery-symposium.org/" rel="nofollow external" class="bo">3rd annual pediatric innovation 
    symposium</a> at the Newseum in DC . Companies are pitching
     for winning the Sheikh Zayed prizes for pediatric device innovation. 
    Expert panels are discussing various aspects of integrating innovation, 
    technology, regulatory, legal, risk and funding aspects of bringing 
    devices to market.<br><br>Two top prized of $50,000 each will be awarded to the winning presentations.<br></div>
]]>
</Body>
<Summary>On October 23rd, Dr. Rao's Sensors class is attending the 3rd annual pediatric innovation  symposium at the Newseum in DC . Companies are pitching  for winning the Sheikh Zayed prizes for...</Summary>
<Website>http://cast.umbc.edu</Website>
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<Title>UMBC iGEM Team wins Bronze Medal</Title>
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<![CDATA[
    <div class="html-content"><div>Congratulations to the student-run International Genetically Engineered Machine (iGEM) team for winning a bronze medal at the <a href="http://2015.igem.org/Giant_Jamboree" rel="nofollow external" class="bo">2015 Giant Jamboree </a>which took place September 24-28 in Boston, MA. Shown in this picture from left to right are Sam Keating, Dr. Cynthia Wagner, May Li, and Pranesh Navarathna. Both Sam and Pranesh are students in the department of Chemical, Biochemical, and Environmental Engineering.</div><div><br></div><div>The International Genetically Engineered Machine (iGEM) competition is a research opportunity for undergraduates in the field of synthetic biology.  Undergraduates participating in this competition design a synthetic biology project during the academic year, implement the project during the summer months, and presenting the results in the fall at MIT’s Giant Jamboree.  The Jamboree is an annual event where iGEM teams from high schools and universities from all over the world come to present their synthetic biology projects.  On September 24, members of UMBC’s International Genetically Modified Machine team traveled to Boston to present their research at MIT’s Giant Jamboree. UMBC’s iGEM team presented a copper bioremediation project.  Copper is a major contaminant in many bodies of water including the Chesapeake Bay.  The UMBC iGEM team had two goals: to engineer E. coli that could withstand high copper concentrations, and to increase E. coli’s ability to uptake copper from the environment. In order to accomplish this, the UMBC iGEM team engineered E. coli to overexpress a protein called metallothionein which is capable of binding eleven copper atoms and also capable of neutralizing toxic free radicals that are generated by an overabundance of copper.   Preliminary data showed promise with both increased survivability and increased uptake in E. coli.  Eventually, this research could lead to a waste management technique that uses engineered E. coli to remove copper contaminants from the environment. The team was awarded a bronze medal for demonstrating a real world need for copper remediation and sufficient methods and documentation of the work done this summer.</div><div><br></div><div><br></div></div>
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<Summary>Congratulations to the student-run International Genetically Engineered Machine (iGEM) team for winning a bronze medal at the 2015 Giant Jamboree which took place September 24-28 in Boston, MA....</Summary>
<Website>http://retrieverweekly.umbc.edu/?p=4219</Website>
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<PostedAt>Thu, 08 Oct 2015 07:58:10 -0400</PostedAt>
<EditAt>Sun, 11 Oct 2015 21:40:24 -0400</EditAt>
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