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<NewsItem contentIssues="true" id="146446" important="true" status="posted" url="https://my3.my.umbc.edu/posts/146446">
<Title>Adjusted dinner hours at True Grit's</Title>
<Tagline>Due to the weather conditions dinner hours are adjusted</Tagline>
<Body>
<![CDATA[
    <div class="html-content">Due to the anticipated deteriorating weather conditions, we adjusted our dinner hours to 4:30 pm - 6:30 pm. Guests will have the option of dining in or taking their meal to go during dinner. </div>
]]>
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<Summary>Due to the anticipated deteriorating weather conditions, we adjusted our dinner hours to 4:30 pm - 6:30 pm. Guests will have the option of dining in or taking their meal to go during dinner. </Summary>
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<PostedAt>Mon, 06 Jan 2025 10:01:59 -0500</PostedAt>
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<NewsItem contentIssues="true" id="146445" important="false" status="posted" url="https://my3.my.umbc.edu/posts/146445">
<Title>Intern of the Week: Prabhakar Yasaswi Venuthurupalli</Title>
<Tagline>Check out Prabhakar's internship!</Tagline>
<Body>
<![CDATA[
    <div class="html-content"><span><p><span><strong>Name</strong></span><span>:</span><span> Prabhakar Yasaswi Venuthurupalli</span><span><br><br></span></p>
    <p><span><strong>Pronouns</strong></span><span>:</span><span> He/Him</span><span><br><br></span></p>
    <p><span><strong>Semester of Internship</strong></span><span>: </span><span>Fall 2024</span><span><br><br></span></p>
    <p><span><strong>Major</strong></span><span>: </span><span>Chemical &amp; Biochemical Engineering</span><span><br><br></span></p>
    <p><span><strong>Current Class Level</strong></span><span>: </span><span>Master's Student</span></p>
    <p><span><strong>This semester I completed a(n)...</strong></span><span><br></span><span>Co-op</span></p>
    <p><span><strong>Internship, Co-op, or Research Site (Company/Organization Name):</strong></span><span><br></span><span>WuXi Biologics</span></p>
    <p><span><strong>Location of the Organization (City, State):</strong></span><span><br></span><span>New Jersey</span></p>
    <p><span><strong>Title of position:</strong></span><span><br></span><span>Associate Scientist Co-op</span></p>
    <p><span><strong>Tell us about your internship, co-op, or research opportunity, including your day-to-day responsibilities:</strong></span><span><br></span><span>In my CO-OP role within Downstream Process Development, I am responsible for purifying large biomolecules, including monoclonal antibodies and bispecific antibodies, through advanced chromatography (using AKTA systems) and UF/DF filtration techniques. My work is centered around optimizing these processes to enhance protein recovery while maintaining high product quality and scalability for commercial production. Operating on a GMP floor, I strictly adhere to GxP guidelines, follow SOPs, and engage in cross-functional collaboration to ensure all workflows meet regulatory compliance. Daily, I perform equipment calibration, maintenance, and monitoring of key parameters to uphold process consistency. I also follow Good Laboratory Practices (GLP) and industrial safety protocols rigorously to maintain a safe working environment. My role requires meticulous documentation of quality control data, which supports traceability and provides insights for continual improvement across development processes.</span></p>
    <p><span><strong>Describe the process of obtaining your position. When did you hear of the position and submit your application?</strong></span><span><br></span><span>I first learned about my current CO-OP opportunity in Downstream Process Development after meeting Dr. Frank Li, Executive Director at WuXi, during his guest lecture at UMBC. His presentation focused on career growth in biotech for chemical engineers, and afterward, I was fortunate to have an in-depth conversation with him about the transition from academia to industry and the essential skills needed for success in biotech. Encouraged by his advice, I submitted my application for the CO-OP position, tailoring my resume to highlight my experience in downstream processing and adherence to GMP standards. Shortly after, I was invited to begin a multi-stage interview process, where I was able to further elaborate on my technical expertise, particularly in protein purification and process optimization. My conversations with the interviewers, coupled with Dr. Li’s encouragement, led to an offer for the CO-OP position, marking an invaluable step forward in my career journey.</span></p>
    <p><span><strong>What resources did you use to find your current experience?</strong></span><span><br></span><span>UMBC Career Center, Career Fairs, Networking events (UMBC Connects, Info Sessions, Arts With a Purpose, etc.), Alumni Networking, Student Organizations/Scholar Groups, Faculty Connections, Handshake, LinkedIn</span></p>
    <p><span><strong>What have you enjoyed the most about your position and organization?</strong></span><span><br></span><span>What I’ve enjoyed most about my CO-OP position at WuXi is the hands-on experience I’ve gained in downstream process development, working with advanced techniques like chromatography and UF/DF to improve protein purification. Each day offers a new challenge and learning opportunity, allowing me to apply my academic knowledge in a practical, impactful way while deepening my understanding of GMP and regulatory standards. The team culture at WuXi has also been a highlight. I’ve found the collaborative environment and cross-functional support incredibly enriching. The organization emphasizes continuous learning and innovation, creating an atmosphere where I feel encouraged to grow professionally and personally.</span></p>
    <p><span><strong>How do you believe you have made an impact through your work?</strong></span><span><br></span><span>I believe I have made a significant impact through my work in downstream process development by optimizing purification techniques and enhancing overall process efficiency. For instance, my efforts in refining chromatography and UF/DF methods have led to a 20% improvement in protein recovery, which not only ensures higher product quality but also contributes to the scalability of our processes for commercial production. Additionally, by actively adhering to GMP standards and participating in cross-functional collaboration, I have helped maintain a culture of compliance and continuous improvement within the team. My focus on data analysis and documentation has also reinforced the importance of traceability and quality control in our operations, ensuring that we meet regulatory requirements and maintain the integrity of our processes. Overall, I feel my contributions have supported both the technical and operational goals of the organization, helping to drive our projects forward successfully.</span></p>
    <p><span><strong>What advice would you give to another student who is seeking an internship or similar experience?</strong></span><span><br></span><span>For students seeking an internship or similar experience, my key advice would be to start early and actively explore opportunities that align with your career interests. Begin by utilizing your university’s career resources, attending career fairs, and networking with professionals in your field. Tailor your resume and cover letter to highlight relevant coursework, projects, and skills that make you a strong candidate. Don't hesitate to reach out to professors and industry contacts for guidance and potential leads. Moreover, be proactive in preparing for interviews by researching the organization and practicing common interview questions, particularly those related to your technical skills and experiences. During interviews, express your genuine interest in the company and its work, and be prepared to discuss how you can contribute to their goals. Finally, remain open-minded about the roles you apply for; even positions that may not seem like a perfect fit can provide valuable experience and insights into the industry. Embrace the learning opportunities that come your way, as they can pave the path for future success.</span></p>
    <span><strong>Please provide a short reflection or quote about what you liked most about your position / earning internship credit / working with the Career Center:</strong></span><span><br></span><span>What I liked most about my CO-OP position was the opportunity to apply my academic knowledge in a hands-on setting, working on innovative purification techniques that directly impact product quality. The Career Center played a vital role in my journey by providing valuable resources, networking opportunities, and guidance that helped me refine my resume and prepare for interviews, ultimately leading me to this enriching experience.</span></span></div>
]]>
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<Summary>Name: Prabhakar Yasaswi Venuthurupalli    Pronouns: He/Him    Semester of Internship: Fall 2024    Major: Chemical &amp; Biochemical Engineering    Current Class Level: Master's Student  This...</Summary>
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<Sponsor>Career Center</Sponsor>
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<PostedAt>Mon, 06 Jan 2025 00:01:02 -0500</PostedAt>
<EditAt>Fri, 31 Jan 2025 09:32:30 -0500</EditAt>
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<NewsItem contentIssues="true" id="146444" important="true" status="posted" url="https://my3.my.umbc.edu/posts/146444">
<Title>UMBC Transit Closed ~ Winter Snow Storm - 01.06.25</Title>
<Tagline>Stay tuned for updates on further weekday bus service.</Tagline>
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    <p><span>Dear Retrievers and Valued Transit Riders,</span></p>
    <p><span>Due to the incoming winter storm, UMBC Transit will be closed on </span><strong>Monday, January 6, 2025</strong><span>. The safety of our riders and staff remains our top priority as we navigate these weather challenges.</span></p>
    <p><span>We will assess road conditions </span><span>on an hourly basis</span><span> to determine our operational status for </span><strong>Tuesday, January 7, 2025</strong><span>. Please stay tuned for updates regarding any changes to our services.</span></p>
    <p><span>For the latest weather-related transit advisories and updates, visit </span><strong><a href="https://umbc.edu/about/inclement-weather-emergency-closing-policy/#:~:text=In%20the%20event%20of%20inclement,special%20announcement%20will%20be%20made." rel="nofollow external" class="bo">the Inclement Weather and Emergency Closing Guide</a></strong><span>. You may also call the campus status hotline at </span><strong>410-455-6789.</strong></p>
    <p><strong>Transit Tips for Safe Travel:</strong></p>
    <ul>
    <li><span>Dress warmly and prepare for slick surfaces due to potential snow or ice.</span></li>
    <li><span>Allow extra time to reach your bus stop and exercise caution when boarding UMBC buses.</span></li>
    <li><span>Avoid running to catch the bus, especially during inclement weather.</span></li>
    </ul>
    <p><span>We appreciate your patience and understanding as we work to prioritize safety during this time. For any additional assistance, </span><span>please contact us</span><span> at </span><strong>410.455.2454</strong><span> or </span><strong><a href="mailto:transit@umbc.edu">transit@umbc.edu</a></strong><span>.</span></p>
    <p><span><br></span></p>
    <p><span>Stay safe,</span></p>
    <p><em>Your Transit Team ~ Driving Student Success</em></p>
    </div></div></div>
]]>
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<Summary>Dear Retrievers and Valued Transit Riders,  Due to the incoming winter storm, UMBC Transit will be closed on Monday, January 6, 2025. The safety of our riders and staff remains our top priority as...</Summary>
<Website>http://transit.umbc.edu</Website>
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<NewsItem contentIssues="true" id="146443" important="false" status="posted" url="https://my3.my.umbc.edu/posts/146443">
<Title>The RAC is closed January 6, 2025 due to inclement weather.</Title>
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<![CDATA[
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    <span><span>Due to the anticipated inclement weather, the RAC will be closed on Monday, January 6. </span></span><span>#RACclosure</span>
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]]>
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<Summary>Due to the anticipated inclement weather, the RAC will be closed on Monday, January 6. #RACclosure</Summary>
<Website>https://recreation.umbc.edu/inside-recreation/recreation-hours-the-rac/</Website>
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<Sponsor>Recreation at the RAC</Sponsor>
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<NewsItem contentIssues="false" id="146442" important="false" status="posted" url="https://my3.my.umbc.edu/posts/146442">
<Title>UMBC Pre-Pharm Shadowing and GBMs</Title>
<Body>
<![CDATA[
    <div class="html-content">
    <div>Hello Pre-pharmers, and happy new year! </div>
    <div><br></div>
    <div>I just wanted to notify you guys about a google form we sent out, through email to see what day you all prefer for our GBMs next semester. Optionally, if anyone is interested in shadowing current e-board members, you can state your interest on that form as well. The form will be open until January 12th.</div>
    <div><br></div>
    <div> We hope to hear from you all soon. Have a great winter break!</div>
    <div><br></div>
    </div>
]]>
</Body>
<Summary>Hello Pre-pharmers, and happy new year!      I just wanted to notify you guys about a google form we sent out, through email to see what day you all prefer for our GBMs next semester. Optionally,...</Summary>
<Website>https://docs.google.com/forms/d/e/1FAIpQLSf1o2BBby6_FukQmSN6yHuRPqoWQBarplMO-vOD8vqWjcmkIg/viewform</Website>
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<NewsItem contentIssues="false" id="146441" important="false" status="posted" url="https://my3.my.umbc.edu/posts/146441">
<Title>From Texas to Maryland and Back Again</Title>
<Body>
<![CDATA[
    <div class="html-content">
    <p>“We shall not cease from exploration, and the end of all our exploring will be to arrive where we started and know the place for the first time.” – T.S. Eliot</p>
    
    
    
    <p>It’s 2021, senior year of high school, and as the COVID-19 pandemic continues to surge we sit anxiously at our computers awaiting responses from the universities and colleges we’ve applied to. Few students dare to break from tradition, choosing instead to follow the well-trodden paths of their parents, grandparents, siblings, or cousins. In Texas—especially at this small Catholic school—tradition carries immense weight, shaping the choices of most graduates. </p>
    
    
    
    <p>Because of this, it’s no surprise that when a peer decides to go to an out-of-state school, it’s met with shock and skepticism. “<em>Are you sure you want to move so far away?”</em> they ask, voices tinged with disbelief. <em>“How could you leave your family? What are you even going to do out there? Isn’t it easier to just stay here?”</em> These questions often carry an undertone of judgment, as if breaking away from the familiar is a betrayal of the community or an unnecessary risk. </p>
    
    
    
    <p>I was no exception to these questions when I announced that I would be going to the University of Maryland, Baltimore County, (UMBC). Still, I knew deep down that Texas had given me all it could. Despite coming from a liberal family, we couldn’t escape the suffocating grip of conservatism that shaped so much of life in San Antonio. In my 18 years there, I was taught to love Jesus and my family, to believe that abortion was the ultimate sin, and that rape could never result in pregnancy. Texas seemed determined to isolate itself from the rest of the world, and I realized no one around me was going to show me what lay beyond its borders. If I wanted to see the world for what it truly was, I had to leave and discover it with my own eyes.</p>
    
    
    
    <p>It wasn’t easy. I often found myself going to great lengths to reassure people that, despite the stereotypes, not everyone in Texas was a bigot. It was true that my life experiences had been limited, but more than anything, I wanted to learn and grow. Being away from my family was a constant challenge. While I formed wonderful friendships, my peers had the privilege of going home after a tough week or celebrating their birthdays with loved ones. My visits were restricted to Thanksgiving and Christmas breaks, and the ache of homesickness sometimes made me question my decision. Yet, I knew deep down that this was a path I had to follow—a necessary step to discover more about myself and the world, no matter how hard it was.</p>
    
    
    
    <p>For the first time in my life, I wasn’t required to wear a school uniform, and people asked me about my pronouns and sexuality—things that had never been part of the conversation back home. Here, there was no assumption that I was straight or that I had to stick to she/her pronouns. It was liberating in a way I hadn’t imagined. Every weekend, I called home, brimming with excitement about what I was studying and experiencing. I’ll never forget how thrilled I was to discover new ideas and perspectives that challenged everything I thought I knew.</p>
    
    
    
    <p>Reproductive health, in particular, was something I had no idea about when I arrived in Maryland. Growing up in Texas, I was steeped in a culture that avoided honest conversations about sex, contraception, and bodily autonomy. Misinformation shaped my understanding, from the stigmatization of abortion to outright falsehoods about pregnancy and assault. At UMBC, I encountered a starkly different reality—one where access to accurate information and open dialogue about reproductive health was not only encouraged but normalized.</p>
    
    
    
    <p>Learning about comprehensive sex education, the science of reproduction, and the policies that impact reproductive rights empowered me to think critically and advocate for myself and others. It has been a transformative experience, allowing me to see how much I had been denied back home.</p>
    
    
    
    <p>UMBC felt like an entirely different world, one that revealed just how sheltered my life in Texas had been. I was thrilled to finally learn the information I had missed out on growing up—knowledge that felt empowering and long overdue. More than anything, I wanted to return home and share what I had discovered, to challenge the misconceptions that had shaped so much of my upbringing. I realized how fortunate I was to have the opportunity to attend college out of state, knowing that not everyone has the privilege to explore life beyond the boundaries of their hometown.</p>
    
    
    
    <p>Four years later, now in my senior year of college, I am planning for life after graduation—a future that once felt bright and full of promise but now seems clouded by the aftermath of the recent presidential election and its implications. Returning to a conservative state like Texas feels overwhelming, knowing I may encounter skepticism or resistance from those with deeply different views. As a woman, I’m acutely aware of the rights that have been stripped away, and the thought of going back fills me with fear. Yet, my love for my family and my desire to support girls like me—those who don’t have the option to leave—outweigh my hesitation. I want to make Texas a better place for them, a place where they can thrive despite the challenges.</p>
    
    
    
    <p>When I share my decision to return to Texas, the reactions from friends and colleagues are often a mix of shock and fear. <em>“Why would you go back there?”</em> they ask, eyes wide, their voices filled with concern. I can’t blame them for their alarm—after all, I’ve spent years speaking openly about the challenges of growing up in a conservative state and the liberating experiences I’ve had here in Maryland. But despite their worry, my decision feels right. Texas shaped me, for better or worse, and I can’t turn my back on the place or the people who are still there, navigating the same struggles I once faced. Yes, moving back is daunting, but it’s also a chance to bring the knowledge I’ve gained and the perspective I’ve developed to a community that needs it. And while leaving the supportive and progressive environment I’ve built in Maryland is bittersweet, I know that going back is not a step backward. It’s a step toward creating change and making my home a place where others like me can see a future worth staying for.</p>
    
    
    
    <p>I understand that meaningful change won’t happen overnight, but I truly believe that progress is possible. </p>
    </div>
]]>
</Body>
<Summary>“We shall not cease from exploration, and the end of all our exploring will be to arrive where we started and know the place for the first time.” – T.S. Eliot      It’s 2021, senior year of high...</Summary>
<Website>https://womenscenteratumbc.wordpress.com/2025/01/04/from-texas-to-maryland-and-back-again/</Website>
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<Tag>feminism</Tag>
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<Tag>texas</Tag>
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<Sponsor>Women's Center</Sponsor>
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<NewsItem contentIssues="false" id="146440" important="false" status="posted" url="https://my3.my.umbc.edu/posts/146440">
<Title>ESA Mentee Application - Spring 2025 - Application Due 1/12</Title>
<Tagline>Interested in becoming an ESA Board Member?</Tagline>
<Body>
<![CDATA[
    <div class="html-content">
    <span>This application is for students who are interested in being a future ESA Board member. You will be expected to attend all weekly ESA Board meetings and events beginning in Feburuary 2025. Mentees will be mentored by the person holding the position they're interested in. </span><div>
    <div><br></div>
    <div>Submit your application by <strong>January 12th, 2024. </strong>
    </div>
    </div>
    <div><strong><br></strong></div>
    <div><a href="https://docs.google.com/forms/d/e/1FAIpQLSeNE-EJa4Brm_5efQ4U0CanvkgSKhobkPNFQ4UBTq-iMAnQMg/viewform" rel="nofollow external" class="bo">https://my3.my.umbc.edu/groups/egyptianstudentassociation/posts/146226/4e41c/d16dcc568c6fa229b65453d3bceb66db/web/link?link=https%3A%2F%2Fdocs.google.com%2Fforms%2Fd%2Fe%2F1FAIpQLSeNE-EJa4Brm_5efQ4U0CanvkgSKhobkPNFQ4UBTq-iMAnQMg%2Fviewform%3Fusp%3Dheader</a></div>
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]]>
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<Summary>This application is for students who are interested in being a future ESA Board member. You will be expected to attend all weekly ESA Board meetings and events beginning in Feburuary 2025. Mentees...</Summary>
<Website>https://my3.my.umbc.edu/groups/egyptianstudentassociation/posts/146226/4e41c/d16dcc568c6fa229b65453d3bceb66db/web/link?link=https%3A%2F%2Fdocs.google.com%2Fforms%2Fd%2Fe%2F1FAIpQLSeNE-EJa4Brm_5efQ4U0CanvkgSKhobkPNFQ4UBTq-iMAnQMg%2Fviewform%3Fusp%3Dheader</Website>
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<NewsItem contentIssues="true" id="146438" important="false" status="posted" url="https://my3.my.umbc.edu/posts/146438">
<Title>ESI scientists and graduate students present at APOLO and AGU conferences</Title>
<Body>
<![CDATA[
    <div class="html-content">
    <div>ESI members participated in two conferences this past fall: the Advancements in Polarimetric Observations (APOLO) in Kyoto, Japan, from November 18 -22, 2024 and the American Geophysical Union (AGU) in Washington, DC from December 8 -13, 2024. </div>
    <div><br></div>
    <div>
    <a href="https://physics.umbc.edu/research/atmospheric/" rel="nofollow external" class="bo">UMBC ATPH</a> graduate students <a href="https://esi.umbc.edu/graduate-research-assistants/#Sienkiewicz" rel="nofollow external" class="bo">Noah Sienkiewicz</a>, <a href="https://esi.umbc.edu/graduate-research-assistants/#Smith" rel="nofollow external" class="bo">Rachel Smith</a>, <a href="https://esi.umbc.edu/graduate-research-assistants/#Jayasinghe" rel="nofollow external" class="bo">Nirandi Jayasinghe</a>, and <a href="https://esi.umbc.edu/graduate-research-assistants/#Regmi" rel="nofollow external" class="bo">Greema Regmi</a> presented at APOLO and the latter three also at AGU. Mr. Sienkiewicz showed the latest results in the calibration of <a href="https://esi.umbc.edu/harp2-project/" rel="nofollow external" class="bo">HARP2</a>, and Ms. Smith discussed a new cloud property retrieval technique applied to HARP2 data. Ms. Jayasinghe presented research on the interactions between aerosols and clouds, and Ms. Regmi used two different instruments, a polarimeter and a lidar, to tease out finer details about aerosol-shaped properties. </div>
    <div><br></div>
    <div>
    <a href="https://esi.umbc.edu/members-a-z/#McBride" rel="nofollow external" class="bo">Dr. Brent McBride</a>, research scientist at ESI, co-convened a special interdisciplinary session on the science of the <a href="https://science.nasa.gov/mission/pace/" rel="nofollow external" class="bo">NASA PACE</a> mission at AGU, alongside <a href="https://gestar2.umbc.edu/directory/researchers-a-f/#Craig" rel="nofollow external" class="bo">Dr. Susanne Craig</a> (616/UMBC/GESTAR II), Skye Caplan (616/GSFC), and Dr. Bastiaan van Diedenhoven (SRON) on December 10, 2024. This session focused on current research in clouds, aerosols, land, ocean, modeling efforts, and algorithm development in support of PACE. </div>
    <div><br></div>
    <div>In this session, ESI scientists <a href="https://esi.umbc.edu/members-a-z/#Puthukkudy" rel="nofollow external" class="bo">Dr. Anin Puthukkudy</a> presented global HARP2 aerosol retrievals and <a href="https://esi.umbc.edu/members-a-z/#Xu" rel="nofollow external" class="bo">Dr. Xiaoguang Xu</a> discussed how to use HARP2 data to differentiate ice from liquid water clouds. ESI project scientist <a href="https://esi.umbc.edu/members-a-z/#Remer" rel="nofollow external" class="bo">Dr. Lorraine Remer</a> speculated on the future of aerosol remote sensing, Dr. McBride showed how PACE can be used to study hurricane properties, and ESI director <a href="https://esi.umbc.edu/members-a-z/#Martins" rel="nofollow external" class="bo">Dr. J. Vanderlei Martins</a> proposed a new method for retrieving aerosol radiative forcing from HARP2 multi-angle data. </div>
    <div><br></div>
    <div>Visit us at the ESI hallway on the third floor of the <a href="https://umbc.edu/about/visit/directions/" rel="nofollow external" class="bo">UMBC Physics building</a> to learn more about HARP2, PACE, and our current research directions.</div>
    <div><br></div>
    <div><img src="https://my3.my.umbc.edu/system/shared/attachments/news/000/146/438/1af939a4e94043bd8c02a1f6ac7d1043/APOLO_japan.jpg" style="max-width: 100%; height: auto;"></div>
    <div><br></div>
    <div>
    <em>Photo, left to right:</em> UMBC ATPH graduate students Nirandi Jayasinghe and Rachel Smith, ESI director Dr. J. Vanderlei Martins, and UMBC ATPH graduate students Greema Regmi and Hannah Seppala stand next to a woman in traditional kimono attire at the APOLO conference in Kyoto, Japan. <em>(Photo credit: R. Smith/ESI)</em>
    </div>
    </div>
]]>
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<Summary>ESI members participated in two conferences this past fall: the Advancements in Polarimetric Observations (APOLO) in Kyoto, Japan, from November 18 -22, 2024 and the American Geophysical Union...</Summary>
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<Sponsor>Earth and Space Institute</Sponsor>
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<NewsItem contentIssues="false" id="146439" important="false" status="posted" url="https://my3.my.umbc.edu/posts/146439">
<Title>Physical Office Closure | Monday January 6th</Title>
<Body>
<![CDATA[
    <div class="html-content">
    <span>In anticipation of the inclement weather, Residential Life will extend its remote model through Monday, January 6, 2025.  The office will be physically closed, but staff will be working remotely.</span><br><br><span>As a reminder, Residential Life will physically reopen on Tuesday, January 7, 2025 with modified hours (9 a.m.- 4:30 p.m.) through January 17, 2025.  Regular office hours will resume on Tuesday, January 21, 2025.</span><br><br><span>If you need assistance and are not sure who to reach out to, please call 410-455-2591 or submit an RT Ticket (</span><a href="http://reslife.umbc.edu/contact-us" rel="nofollow external" class="bo">reslife.umbc.edu/contact-us</a><span>).</span>
    </div>
]]>
</Body>
<Summary>In anticipation of the inclement weather, Residential Life will extend its remote model through Monday, January 6, 2025.  The office will be physically closed, but staff will be working remotely....</Summary>
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<PostedAt>Fri, 03 Jan 2025 14:55:38 -0500</PostedAt>
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<NewsItem contentIssues="true" id="146436" important="false" status="posted" url="https://my3.my.umbc.edu/posts/146436">
<Title>NEW PUBLICATION: Aspergillus nidulans cell wall integrity kinase, MpkA, impacts cellular phenotypes that alter mycelial-material mechanical properties</Title>
<Tagline>Kelsey Gray, Ph.D. Candidate Marten Lab with Dr. Marten</Tagline>
<Body>
<![CDATA[
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    <h3>Authors: </h3>
    <div>
    <strong>Kelsey Gray, Harley Edwards, Alexander G. Doan, Walker Huso, JungHun Lee,</strong> Wanwei Pan, <strong>Nelanne Bolima, Meredith E. Morse, Sarah Yoda</strong>, Isha Gautam, Steven D. Harris, Marc Zupan, Tuo Wang, Tagide deCarvalho &amp; <strong>Mark R. Marten</strong>
    </div>
    <div><strong><br></strong></div>
    <h3>Title: </h3>
    <div><strong><em>Aspergillus nidulans</em> cell wall integrity kinase, MpkA, impacts cellular phenotypes that alter mycelial-material mechanical properties</strong></div>
    <div><br></div>
    <div>
    <h3>Abstract:</h3>
    <div>
    <p>Mycelial materials are an emerging, natural material made from filamentous fungi that have the potential to replace unsustainable materials used in numerous commercial applications (e.g., packaging, textiles, construction). Efforts to change the mechanical properties of mycelial-materials have typically involved altering growth medium, processing approaches, or fungal species. Although these efforts have shown varying levels of success, all approaches have shown there is a strong correlation between phenotype (of both fungal mycelia and mycelial material’s assembly) and resultant mechanical properties. We hypothesize that genetic means can be used to generate specific fungal phenotypes, leading to mycelial materials with specific mechanical properties. To begin to test this hypothesis, we used a mutant of the model filamentous fungus, <em>Aspergillus nidulans</em>, with a deletion in the gene encoding the last kinase in the cell wall integrity (CWI) signaling pathway, <em>mpkA</em>. We generated one set of mycelial materials from the <em>ΔmpkA</em> deletion mutant (A1404), and another from its isogenic parent (A1405; control). When subjected to tensile testing, and compared to material generated from the control, <em>ΔmpkA</em> material has similar elastic modulus, but significantly increased ultimate tensile strength, and strain at failure. When subjected to a fragmentation assay (i.e., resistance to shear-stress), the <em>ΔmpkA</em> material also had higher relative mechanical strength. To determine possible causes for this behavior, we carried out a comprehensive set of phenotype assessments focused on: three-dimensional structure, hyphal morphology, hyphal growth behaviors, and conidial development. We found, compared to the control, material generated from the <em>ΔmpkA</em> mutant manifests significantly less development, a modified cell wall composition, larger diameter hyphae, more total biomass, higher water capacity and more densely packed material, which all appear to impact the altered mechanical properties.</p>
    full article: <a href="https://doi.org/10.1186/s40694-024-00191-4" rel="nofollow external" class="bo">https://doi.org/10.1186/s40694-024-00191-4</a>
    </div>
    <div><br></div>
    </div>
    </div>
]]>
</Body>
<Summary>Authors:   Kelsey Gray, Harley Edwards, Alexander G. Doan, Walker Huso, JungHun Lee, Wanwei Pan, Nelanne Bolima, Meredith E. Morse, Sarah Yoda, Isha Gautam, Steven D. Harris, Marc Zupan, Tuo Wang,...</Summary>
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<Tag>grad</Tag>
<Tag>marten</Tag>
<Tag>research</Tag>
<Tag>spring-2025</Tag>
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<Sponsor>Chemical, Biochemical and Environmental Engineering</Sponsor>
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<PostedAt>Fri, 03 Jan 2025 10:50:19 -0500</PostedAt>
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