mark your calendars! UMBC ART WEEK 2012 is happening April 2nd-6th and submission deadlines are in mid-to-late March! more information and marketing coming very soon!

fyi - we’ll be looking for multimedia, film, animation, photography, traditional, installation, 2D, and 3D art + any other art you can think of! share, pass it along, tell all of your friends! we want you, so get excited. 

CSEE Colloquium

An Integrated Machine Learning Framework for Analyzing Protein-Ligand Interaction Data

Dr. Huzefa Rangwala
Assistant Professor, Computer Science & Engineering
George Mason University

1:00 p.m., Friday, February 10, 2012, ITE 325B, UMBC

Proteins have a vast influence on the molecular machinery of life. Stunningly complex networks of proteins perform innumerable functions in every living cell.  Small organic molecules (a.k.a. ligands) can bind to different proteins and modulate (inhibit/activate) their functions. Understanding these interactions provides insight into the underlying biological processes and is useful for designing therapeutic drugs.

In this talk I will describe our work related to the analysis of information associated with proteins and their interacting molecule partners (protein-ligand activity matrix). The underlying hypothesis of our approach is that by extracting information from protein-ligand activity matrix, we are drawing bridges between the structure of chemical compounds (chemical space) and the structure of the proteins and their functions (biological space).  I will present an approach used for mining relational data, especially when the data is sparse and high dimensional. I will also present methods that are based on the principles of multi-task learning and semi-supervised learning.

Huzefa Rangwala is an Assistant Professor at the department of Computer Science & Engineering, George Mason University. He holds affiliate positions with the Department of Bioengineering and the Department of Bioinformatics & Computational Biology. He received his Ph.D. in Computer Science from the University of Minnesota in the year 2008. His core research interests include bioinformatics, machine learning, and high performance computing. Specifically, he is working on developing new data mining algorithms and applying them to the fields of genomics, structural bioinformatics, drug discovery and social media analysis.

Host: Dr. Marie desJardins

Just in time to commemorate the 2nd anniversary of the earthquake that devastated Haiti, leaving 316,000 people dead and millions displaced, an alumni-directed documentary chronicling two brothers’ return to the country has been released for online viewing.

“Lift Up,” which was co-directed by Huguens Jean ’03, ’11, Ph.D., electrical engineering, and Philip Knowlton ’03, visual arts, recently completed a year-long international film festival tour during which is was awarded the Amsterdam Film Fest Van Gogh Award, Documentary Directing and the Williamsburg Film Fest Outstanding Achievement, Feature Documentary award.

The film follows Jean as he and his brother, Clifford Muse, ’11, information systems, returned to Haiti in March 2010 to honor the memory of their grandfather, whose funeral they missed because of the earthquake. Read more about the documentary here.

Just in time to commemorate the 2nd anniversary of the earthquake that devastated Haiti, leaving 316,000 people dead and millions displaced, an alumni-directed documentary chronicling two brothers’ return to the country has been released for online viewing.

“Lift Up,” which was co-directed by Huguens Jean ’03, ’11, Ph.D., electrical engineering, and Philip Knowlton ’03, visual arts, recently completed a year-long international film festival tour during which is was awarded the Amsterdam Film Fest Van Gogh Award, Documentary Directing and the Williamsburg Film Fest Outstanding Achievement, Feature Documentary award.

The film follows Jean as he and his brother, Clifford Muse, ’11, information systems, returned to Haiti in March 2010 to honor the memory of their grandfather, whose funeral they missed because of the earthquake. Read more about the documentary here.