The 16th annual UMBC Prob-Stat Day conference will be held at the University of Maryland Baltimore County on May 9-10, 2025. The program consists of a short course on Principles of functional Magnetic Resonance Imaging by Professor Martin Lindquist of Johns Hopkins University on Friday (May 9, 2025), followed by talks on the rest of May 9, 2025 and all day of May 10, 2025 (Saturday). Details will be available on the conference website soon. The theme of this conference is neurostatistics and other spatio-temporal big data problems.