CBEE Alum Career Discussion with Dr. Patrick Ymele-Leki
Friday, November 6, 2020 · 12 - 1 PM
All current undergraduate and graduate are invited to join us for a discussion and Q & A with Patrick Ymele-Leki, Ph.D., Chair and Professor at Howard University, Department of Chemical Engineering
Meeting Information
Meeting link:
Meeting number: 120 705 4642
Patrick Ymele-Leki, Ph.D.,
Education:
University of Maryland Baltimore County, Chemical Engineering, PhD, 2009
University of Maryland Baltimore County, Chemical Engineering, BS (Summa Cum Laude), 2003
Montgomery College, Chemical Engineering, AS (With Honors), 2001
Faculté Libre de Sciences, Life and Earth Sciences, AS, 1998
Specialty:
Bacterial adhesion, microfluidic systems, biofilm engineering, infectious diseases, drug discovery, high/low throughput screening
Research:
Our long-term goal is to enhance current antimicrobial arsenal and further understanding of complex microbial communities.
Our research program focuses on (i) the development and implementation of high‐ and low- throughput screening assays for the identification of novel small molecules with antimicrobial activity, (ii) the development and characterization of physiologically and industrially relevant multispecies in vitro biofilm models for the identification of potential drug targets, and (iii) the in vivo assessment of cytotoxicity and pharmacokinetics parameters and hypothesis‐driven validation of antimicrobial drug targets for site colonization related to biofilm formation. This approach combines the benefits of physiologically and industrially relevant assays with a target validation approach superior to that typically encountered for either drug discovery screening or biofilm resistance studies.
Current work and collaborative research projects include (i) the investigation of the impact of biofilm structural features (i.e., porosity, diffusional distance, biomass, and biovolume) and physical fluid forces on the efficacy of known antimicrobial agents; (ii) the evaluation of potential antimicrobial challenge mechanisms as a strategy for in situ biofilm control; and (iii) the identification of novel chemical probes and microbial targets and development of novel drug delivery strategies in biofilm settings. Further details are available on our laboratory website
These studies have applications in medical, pharmaceutical, and biotechnological sciences.
For more details: http://www.che.cea.howard.edu/users/pymeleleki
Current CBEE students and Alumni are also encouraged to connect via CBEE’s Linkedin Alumni Page
Current CBEE students and Alumni are also encouraged to connect via CBEE’s Linkedin Alumni Page
Use the online HTML editor tools to compose the content for your website easily.