Colloquium: Dr. John Rogers, Northwestern University
ABSTRACT: Advanced optoelectronic systems capable of intimate integration onto the surface or into the depth of the brain have the potential to accelerate progress in neuroscience research and to spawn new therapies in clinical medicine. Specifically, capabilities for injecting electronics, light sources, photodetectors, multiplexed sensors, programmable microfluidic networks and other components into precise locations of the deep brain and for softly laminating them onto targeted regions of the cortical surface will open up unique and important opportunities in stimulation, inhibition and real-time monitoring of neural circuits. In this talk, we will describe foundational concepts in materials science and assembly processes for these types of technologies, in 1D, 2D and 3D architectures. Examples in system level demonstrations include experiments on freely moving animals with ‘cellular-scale’, injectable optofluidic neural probes for optogenetics research and with bioresorbable, implantable intracranial sensors for treatment of traumatic brain injury.